hollow fiber module production

Membrane filters & modules

Our heart beats for membrane technology!
Choosing the right membrane and module for your desired project is the key to success –
We passionate to find the best solution with you and for you!

Competence & Expertise

Alpha Plan has over 25 years module manufacturing know-how and expertise – from developing and manufacturing a single prototype to producing millions of hollow fiber modules per annum to supplying a complete automated manufacturing line.

Standard hollow fiber filter

Do you have a specific application in mind and you like to test the approach quickly with a standard module? Do you want to get started with your idea and test the basic concept?

Sometimes a standard hollow fiber module “will do the trick”.
And if you require later certain adaptations, we are happy to do so. A choice of our standard membrane filter which we have permanently on stock is listed here:

Ultrafiltration hollow fiber modules
Endotoxin and Water filter module
Gas transfer modules

New! From now on, you can also purchase our high-quality microfilters, ultrafiltration filters and gas transfer filters around the clock in our new online shop.

hollow fiber module manufacture technology
hollow fiber module production

Customised membrane filter

Do you require a special membrane filter which you can´t find here? Do you require a special size of module, different connectors, a different type of membrane? Talk to us, we´ll find a tailored solution for you.

Contract development & manufacturing of membrane filters

Do you require a very specific membrane filter module for a specific application?

Do want us to assemble e.g. a whole cassette system including the membrane module?

Do you require a serial production of over 100,000s modules? Do you even consider setting-up your own manufacturing line to secure the constant supply?

Contact us, our highly-competent project team consistent of medical device and membrane technology engineers will develop the ideal product for you, having while designing it already the large-scale production in mind.

All our modules are developed and manufactured in-house making them a true Made in Germany product. The hollow fiber membranes are either also manufactured in-house or sourced from renown German and Japanese membrane suppliers to offer you a broad selection of modules.

Visual inspection of hollow fiber filter membrane end faces

Depending on the quantity of modules required, we are able to react very flexible on your needs even if you only require some prototypes or small-series. A decision on a manual, semi-automated or automated manufacturing process is making this possible and follows your budget requirements.

The manufacturing happens in a cleanroom under controlled manufacturing environment. It follows ISO-14644-1 class 8-standard in the central manufacturing area and ISO-14644-1 class 6 under the laminar flow hood work benches.

High quality and quality assurance is the baseline of our doing. Our manufacturing team is very skilled and pays attention to every detail. Our certified quality management system ISO 9001:2015 and EN ISO 13485:2016 and our very good customer satisfaction rate is confirming that.

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Filter development and production

In Radeberg we develop and manufacture microfiltration, ultrafiltration and gas transfer filters under clean room conditions for various applications in the medical, biotechnology, life sciences and pharmaceutical industries.

Alpha Plan produces its own standard filters and upon customer request also customer-specific filters.

Endotoxin- und Wasserfiltermodule

Anwendungsbeispiele:

  • Endotoxin- und Pyrogenabtrennung
  • Wasseraufbereitung
  • Umkehrosmose-Wasser
Art. Nr. Produkt Abmessungen (Ø/Länge) m/o Anschlüsse Membran MWCO Anschlüsse Filter bereich Max. Druck Filtrations-kapazität (initiale Durchfluss-Leistung) (+/- 15%, 298 K)
0510117 Endotoxin filter EF-PSH-15 41 / 260 mm Polysulfone 20 kDa  Hose Barb 6.0 mm 1.4 m² 3 Bar 240 l/h
0510118 Endotoxin filter EF-PSL-15 41 / 260 mm Polysulfone 5 kDa Hose Barb  6.0 mm 1.4 m² 3 Bar 15 l/h
0510129 Water filter UF-PSH-15 41 / 260 mm Polysulfone 20 kDa Tube fitting OD 8.0mm 1.4 m² 3 Bar 240 l/h

MWCO – Molecular Weight Cut-Off; ICS – Intra Capillary Space; ECS – Extra Capillary Space; TMP – Trans-membrane pressure, FLC – Female Luer Connector; Ø – Gehäusedurchmesser; Länge – Gehäuselänge ohne Endkappen und Anschlüsse

Ultrafiltration Hohlfasermodule

Anwendungsbeispiele:

  • Upstream Zell- und Proteinkonzentration
  • Downstream bioprocessing, Protein- und Antikörperaufreinigung
  • Perfusionsfilter für Rührkessel- oder Wave-Bioreaktoren
  • Medien- und Pufferfiltration
  • Virenfilter
Art. Nr. Produkt Abmessungen (Ø/Länge) m/o Anschlüsse Membran MWCO Anschlüsse ICS area ECS area Inner volume Outer volume
0510038 Ultra S – 20 kDa 12 / 60 mm Polysulfone 20 kDa FLC 130 cm² 180 cm² 0.9 ml 1.6 ml
0510100 Ultra S – 5 kDa Polysulfone 5 kDa
0510114 Ultra M – 20 kDa 12 / 150 mm Polysulfone 20 kDa FLC 380 cm² 530 cm² 2.2 ml 4.7 ml
0510102 Ultra M – 5 kDa Polysulfone 5 kDa
0510103 Ultra L – 20 kDa 21 / 120 mm Polysulfone 20 kDa FLC 1800 cm² 2500 cm² 10.5 ml 17.5 ml
0510104 Ultra L – 5 kDa Polysulfone 5 kDa
0510113 Ultra XL – 20 kDa 46 / 260 mm Polysulfone 20 kDa Hose Barb 6.0 mm 1.8 m² 2.6 m² 100 ml 220 ml
0510116 Ultra XL – 5 kDa Polysulfone 5 kDa

MWCO – Molecular Weight Cut-Off; ICS – Intra Capillary Space; ECS – Extra Capillary Space; TMP – Trans-membrane pressure, FLC – Female Luer Connector; Ø – Gehäusedurchmesser; Länge – Gehäuselänge ohne Endkappen und Anschlüsse

Gas-Transfer-Module

Anwendungsbeispiele:
  • Sauerstoffanreicherung / Karbonisierung von Flüssigkeiten
  • Entgasung von Flüssigkeiten
  • Bioreaktor-Oxygenatoren
Art. Nr. Produkt Abmessungen (Ø/Länge) m/o Anschlüsse Membran Anschlüsse Innere Oberfläche Äußere Oberfläche Intrakapillar-volumen Extrakapillar-volumen
0510142 GTM S 12 / 60 mm PMP FLC 80 cm² 160 cm² 0.6 ml 1.3 ml
0510143 GTM M 21 / 120 mm PMP FLC 0.10 m² 0.19 m² 6 ml 17 ml
0510144 GTM L 26 / 120 mm PMP FLC 0.15 m² 0.29 m² 9 ml 26 ml
MWCO – Molecular Weight Cut-Off; ICS – Intra Capillary Space; ECS – Extra Capillary Space; TMP – Trans-membrane pressure, FLC – Female Luer Connector; Ø – Gehäusedurchmesser; Länge – Gehäuselänge ohne Endkappen und Anschlüsse